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TITLE: CONTROLLED GENETIC MANIPULATIONS
PUBLISHER: SPRINGER LANGUAGE: ENGLISH
LINK: http://is.gd/pukheQ RELEASE TYPE: RETAIL
FORMAT: PDF RELEASE DATE: 2014.04.14
ISBN: 9781617795336 STORE DATE: 2012
SAVED.MONEY: 102 EURO DISKCOUNT: 02 x 05MB
AUTHOR: MOROZOV, ALEXEI (ED.)
BOOK
The current demand for the development of techniques for
controlled genetic manipulations is driven by the anatomical and
physiological complexity of the brain and by the need for
experimental models that can address this complexity through
selective manipulation of defined components of the system:
specific neuronal populations or selected synapses. In
Controlled Genetic Manipulations, expert researchers present
detailed chapters to supply basic technical information about
controlled genetic manipulations and to provide examples of
creative implementation of this methodology when addressing a
unique biological problem. Some chapters of the book describe the
most recent developments in the basic methodology, which includes
use of Cre-recombinase, methods for delivery of genetic material
into the brain and the use of optogenetics, whereas other
chapters focus on applying these techniques to addressing
particular biological questions like structural and functional
mapping of neuronal circuits, analysis of specific synaptic
connections, modeling or gene therapy of neurological disorders
As part of the Neuromethods series, chapters include key
implementation advice that is crucial for getting optimal
results
Authoritative and practical, Controlled Genetic Manipulations
serves as a valuable guide to a variety of techniques, provided
by many of the pioneers of the approaches
