TITLE: TOXICOLOGY AND EPIGENETICS
PUBLISHER: WILEY LANGUAGE: ENGLISH
LINK:
http://is.gd/jrFETp RELEASE TYPE: RETAIL
FORMAT: PDF RELEASE DATE: 2014.05.26
ISBN: 9781119976097 STORE DATE: 2012
SAVED.MONEY: 228 EURO DISKCOUNT: 02 x 05MB
AUTHOR: SAURA C. SAHU
BOOK
Epigenetics is the study of both heritable and non-heritable
changes in the regulation of gene activity and expression that
occur without an alteration in the DNA sequence. This dynamic and
rapidly developing discipline is making its impact across the
biomedical sciences, in particular in toxicology where epigenetic
differences can mean that different individuals respond
differently to the same drug or chemical
Toxicology and Epigenetics reflects the multidimensional
character of this emerging area of toxicology, describing
cutting-edge molecular technologies to unravel epigenetic
changes, the use of in vivo and in vitro models, as well as the
potential use of toxicological epigenetics in regulatory
environments. An international team of experts consider the
interplay between epigenetics and toxicology in a number of
areas, including environmental, nutritional, pharmacological, and
computational toxicology, nanomaterials, proteomics and
metabolomics, and cancer research
Topics covered include:
* environment, epigenetics and diseases
* DNA methylation and toxicogenomics
* chromatin at the intersection of disease and therapy
* epigenomic actions of environmental arsenicals
* environment, epigenetics and cardiovascular health
* toxicology, epigenetics and autoimmunity
* ocular epigenomics: potential sites of environmental impact in
development and disease
* nuclear RNA silencing and related phenomena in animals
* epigenomics - impact for drug safety sciences
* methods of global epigenomic profiling
* transcriptomics: applications in epigenetic
toxicology
Toxicology and Epigenetics is an essential insight into the
current trends and future directions of research in this rapidly
expanding field for investigators, toxicologists, risk assessors
and regulators in academia, industry and government
